Abstract
Organofluorine compounds have attracted special attention in the field of drug discovery because of their unique properties, which make them important in biomedicinal research. Great attention has been given to novel methodologies that offer promising convenient synthetic protocols to prepare various organofluorine compounds. This chapter highlights the innovative achievements in the development of nucleophilic fluoroalkylation protocols and their application in the synthesis of various biologically important compounds in the past decade.
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