Abstract
Nanoemulsion has been widely used for topical application in the cosmetic industry mainly for skin moisturizing and hydrating purposes. The ease of formulation, handling, and low manufacturing cost have brought this technology to light. Countless advantages of nanoemulsion have been reported, such as better penetration, absorption, and bioavailability enhancement. The most important criterion that needs to be taken into consideration while formulating skin care products using this technology, especially when dealing with phytochemicals as active ingredients in the products, is their safety assessment so that the probability of negative impact can be minimized. Hence this chapter will review the several in vitro and in vivo safety assessments of nanoemulsion as a skin moisturizer, including its principle and the methods implemented for the study. Through this chapter, it is hoped to provide a guideline for better understanding of the subject matter.
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