139 Trace Mineral Source Matters for Weaned Pigs Challenged with Escherichia Coli F18 in Diets without Pharmacological Zinc Oxide

Abstract

Abstract Trace mineral sources in diets without pharmacological zinc oxide (P-ZnO) were evaluated in weaned pigs challenged with Escherichia coli F18. A total of 54 pigs (Choice genetics; West Des Moines, IA), 5.30 ± 0.42kg, were housed in pens (3 pigs/pen) and randomly assigned to 1 of 3 treatments; 1) a diet with methionine-hydroxy-analog chelated trace mineral blend [MHAC; MINTREX trace minerals (Novus International Inc., St. Charles, MO)], 2) a diet with inorganic trace minerals (ITM). MHAC and ITM treatments supplied 100:120:40mg/kg of Zn, Cu, and Mn, respectively, and 3) P-ZnO with 2,500mg/kg (1,800mg/kg of Zn) and 120:40mg/kg of Cu, and Mn, in the ITM form. After 9-d of acclimatization, all pigs were infected with E. coli F18 There were 13 days of post-infection (dpi) as recovery time. One pig per pen was euthanized at 4-dpi and the remaining at 13-dpi for tissue harvest. Data were analyzed using the MIXED procedure of SAS using a contrast between MHAC and ITM and P-ZnO against MHAC and ITM. After acclimation, ADG increased in pigs fed MHAC than ITM (0.190 vs. 0.128kg; P = 0.003). Pigs fed P-ZnO had similar ADG (0.202 kg) to MHAC (P=0.638) but had increased ADG than ITM (P = 0.014). From dpi 0 to 4, there were no differences in ADG between pigs fed MHAC and ITM (-0.002 vs. -0.034kg; P=0.589). Pigs fed P-ZnO increased ADG (0.408 kg) compared with MHAC (P < 0.001) and ITM (P < 0.001). From 5 to 13 dpi, there were no differences in ADG between MHAC and ITM (0.407 vs. 0.352 kg; P = 0.260). Pigs fed P-ZnO had similar ADG (0.427kg) to MHAC (P=0.680) and ITM (P = 0.137). During acclimation, ADFI increased in pigs fed MHAC than ITM (0.150 vs. 0.120kg; P = 0.050). Pigs fed P-ZnO had increased ADFI (0.188kg) than MHAC (P=0.017) and ITM (P = 0.001). From dpi 0 to 4, pigs fed MHAC had increased ADFI than ITM (0.142 vs. 0.074kg; P = 0.005). Pigs fed P-ZnO had increased ADFI (0.321kg) than MHAC (P< 0.001) and ITM (P < 0.001). From 5 to 13 dpi, there were no differences in ADFI between MHAC and ITM (0.536 vs. 0.447kg; P = 0.147). Pigs fed P-ZnO (0.624kg) had similar ADFI to MHAC (P = 0.157) but increased ADFI compared with ITM (P = 0.011). Pigs fed MHAC tended to have an increased final BW than ITM (11.12 vs. 9.74kg; P=0.060). Pigs fed P-ZnO tended to have increased BW (12.48kg) compared with MHAC (P=0.064) and increased BW compared with ITM (P = 0.002). Diarrhea incidence (0 to 4 dpi) was similar between MHAC and ITM (63.9 vs. 66.7%; P = 0.736). Pigs fed P-ZnO had decreased diarrhea incidence (6.9%) compared with MHAC (P < 0.001) and ITM (P < 0.001). In conclusion, adding MHAC enhanced feed intake and growth performance, aiding recovery from weaning and after E. coli infection in pigs fed diets without P-ZnO.