1307 Development of a novel, cellular-level drug uptake quantification pipeline for accurate estimation of fluorescence-conjugated therapeutics: data from the phase 1b/2 open-label study ASP-1929–181

Abstract

BackgroundPhotoimmunotherapy (PIT) is an investigational anticancer treatment platform that combines cell surface binding of an antibody conjugated to a light activatable dye (IRDye® 700DX, IR700) with red-light illumination for selective...