Abstract
Different groups have recently revealed the usefulness of immune cell quantification in peripheral blood to predict response to immune checkpoint inhibitors (ICI). Our team found an association between CD4+ CD27- CD28- T cells and response to ICI in pretreated NSCLC patients (Zuazo M, 2019), however these findings were not applicable in frontline ICI. We evaluated a cohort of untreated NSCLC patients receiving ICI alone or in combination with chemotherapy (CT+IT).
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