Abstract
The year 2022 marks the 100th anniversary of the vitamin D discovery, however, vitamin D insufficiency and deficiency is globally widespread both in Russia and around the world. At the same time, the COVID-19 pandemic poses a serious challenge to global health. To date, more and more evidence is emerging to consider vitamin D deficiency as a modifiable COVID-19 severe course risk factor. Current review presents possible mechanisms behind the immunomodulatory effects of vitamin D, as well as shows the relationship between the vitamin D level and the course of COVID-19. In addition, the therapeutic potential of cholecalciferol supplementation to standard therapy for COVID-19 is being discussed.
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