Abstract
This chapter deals with the preparation of poly(alkyl acrylic) and poly(alkyl cyanocrylic) nanoparticles. Poly(alkyl acrylic) nanoparticles are much more slowly biodegradable than poly(alkyl cyanoacrylate) nanoparticles. Poly(methyl methacrylate) nanoparticles are preferentially produced by emulsifier-free polymerization in aqueous media because detergents may interact with and damage certain biological materials or change the immunological response. Poly(alkyl acrylate) nanoparticles are X-ray amorphous. Poly(alkyl acrylate) nanoparticles normally have a particle size from between 50 and 300 nm. They possess a solid, rather porous polymer matrix of low density. Their density is considerably lower than that of normal polymer beads or rods made with the same monomers. Poly(alkyl cyanoacrylate) nanoparticles are generated by an anionic polymerization mechanism by base induction. Poly(methyl methacrylate) nanoparticles are also biodegradable although very slowly. The most promising application of poly(alkyl cyanoacrylate) nanoparticles seems to be their use as carriers for antitumoral agents.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
