Abstract
Measurements: Jejunal pHi was calculated by the luminal PCO2, obtained with a balloon tonometer, and arterial bicarbonate concentration. Arterial blood samples were taken for analysis of adrenaline (ADR), noradrenaline (NA), angiotensin II (Ang II) and arterial blood gas. SMV blood samples were taken for analysis of lactate/ pylvate acid (sma L/P), and blood gas (PsmvCO2). Results At shock phase, SMA flow decreased to 40% from the baseline (p < 0.01) and pHi decreased from 7.4 ± 0.2 to
Highlights
It is known that intestinal intramucosal pH is a good parameter of tissue perfusion in critical patients
Physiological meaning of pHi value related to other physiological parameter, such as stress hormone, is not well known
The purpose of the study is to clarify the importance of monitoring pHi during hemorrhagic shock in pig model
Summary
It is known that intestinal intramucosal pH (pHi) is a good parameter of tissue perfusion in critical patients. Physiological meaning of pHi value related to other physiological parameter, such as stress hormone, is not well known. The purpose of the study is to clarify the importance of monitoring pHi during hemorrhagic shock in pig model. The relation between pHi, oxygen supply and demand balance at intestinal region and stress hormones are discussed
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