Abstract

To evaluate the safety and efficacy of cholecystokinin-assisted microwave ablation of hepatic tumors near the gallbladder. IRB-approved retrospective review of 4 patients who had received a total of 5 cholecystokinin (CCK)-assisted microwave ablations of hepatic tumors near the gallbladder fossa. Demographic and procedural information was reviewed including diagnosis, technical success, and 3 month follow-up. There was 80% (4/5) technical success with a single patient demonstrating poor gallbladder contractility in response to CCK administration who was later treated successfully with transarterial chemoembolization. There were no major complications with specifically no episodes of gallbladder rupture or any other significant gallbladder injury. One individual had post operative pain successfully managed with intravenous followed by oral narcotics. Finally, a single patient had residual versus recurrent enhancement on initial 3 month follow-up study and successfully underwent repeat CCK-assisted microwave ablation with no evidence of disease on repeat follow-up. The gallbladder was fully intact on all follow-up studies. Intravenous administration of cholecystokinin offers safe, effective, and noninvasive assistance in performing microwave ablation of hepatic tumors near the gallbladder.

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