Abstract

No. 410 Risk factors for major complications during percutaneous microwave ablation of hepatic tumors E. Dayan, J. Song, E. Kim, R.S. Patel, S.F. Nowakowski, R. A. Lookstein, A.M. Fischman; Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY Purpose: To identify risk factors for development of major complications using percutaneous microwave ablation (MWA) in the treatment of liver tumors. Materials and Methods: Over a 28 month period, 147 patients with unresectable liver tumors (39 women, 108 men; mean age 67) underwent 164 percutaneous CT guided MWA procedures using the Certus 140 2.45GHz gas cooled probe (Neuwave Medical, Madison, WI). A retrospective analysis was performed to review tumor characteristics as well as technical and clinical outcomes. Follow-up consisted of a clinic visit and CT or MRI at 1 month and every 3-4 months thereafter. Chi- square analysis and two sample t-test were performed to identify whether any tumor or patient related variables were associated with development of major complications. Results: A total of 164 tumors were treated (median size 1.8 cm; 0.6-8.2). Tumor size included: o3cm 142/164 (87%), 3- 5cm -20/164 (12%), 45cm 2/164 (1%). Tumor pathology included: 148/164 (90%) hepatocellular carcinoma and 16/164 (10%) liver metastases. Mortality was 0% at 30 and 90 days. Median length of hospital stay was 1 day (range 0-17 days). The most common major complication was pneumothorax requiring chest tube in 7/147 (5%) patients.The second most common major complication was post procedure pulmonary edema requiring intubation in 3/147 (2%) patients. Tumor size, Child- Pugh score, number of ablation sessions, prior hepatic resection and transarterial chemoembolization were not associated with a higher rate of major complications (p40.05). However, a trend is noted of patients who developed one major complication were more likely to develop additional major complications. Conclusion: Percutaneous MWA is a safe method to treat unresectable liver tumors with a low rate of major JVIR ’ Posters and Exhibits S179 P oters nd Exibits

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