Abstract
The aim of the study is to assess the potential cytoprotective properties of extracts in northern berries: common cranberries (Vaccinium oxycoccus L.), bilberries (Vaccinium myrtillus L.), lingonberries (Vaccinium vitis-idaea L.) and blueberries (Vaccinium uliginosum L.) on cell cultures in vitro. Material and methods. For the extracts of these fruits quantitative composition of the main groups of polyphenols is characterized and the level of antiradical activity in the ABTS test is determined. The study results of the effects on cell viability of extracts in the cytotoxicity test are described. Results. It is established that in the primary culture of rabbit alveolar macrophages and the passaged culture of human embryonic kidney cells (HEK293), the studied extracts do not possess own cytotoxicity and prevent the development of the cytotoxic effect of doxorubicin but possess cytoprotective potential.
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