Abstract
ЕФЕКИ БЛОКАТОРА ТРИМЕТИЛАМІН-N-ОКСИДУ В ПОЄДНАННІ З АНТИХОЛІНЕСТЕРАЗНИМ ЗАСОБОМ У ХВОРИХ НА ЦУКРОВИЙ ДІАБЕТ 2-ГО ТИПУ
Highlights
Мета дослідження – оцінити ефективності Ипигриксу самостійно та у комбінації з Мілдронатом у пацієнтів із цукровим діабетом 2-го типу, що страждають на діабетичну полінейропатію, діабетичну енцефалопатію та ішемічну хворобу серця на тлі основного лікування
Materials and methods. 112 selected patients have been divided into 2 groups. 1st group patients, in addition to the basic therapy took Ipidacrine, while the 2nd group patients took a combination of Ipidacrine and Meldonium in addition to their basic treatment
Before and after add-on therapy, the following examinations were conducted: neurological research using the Neuropathy Disability Score (NDS) and endocrinological tests that included the examination of glucose and blood in the fasted state, the level of NOMA-IR index; measuring the level of microalbuminuria, creatinine of blood, glomerular filtration rate, glycated hemoglobin, cortisol and measuring lipid metavolism
Summary
112 selected patients have been divided into 2 groups. 1st group patients, in addition to the basic therapy took Ipidacrine, while the 2nd group patients took a combination of Ipidacrine and Meldonium in addition to their basic treatment. 112 selected patients have been divided into 2 groups. 1st group patients, in addition to the basic therapy took Ipidacrine, while the 2nd group patients took a combination of Ipidacrine and Meldonium in addition to their basic treatment. The treatment course lasted for 1.5 month. Before and after add-on therapy, the following examinations were conducted: neurological research using the Neuropathy Disability Score (NDS) and endocrinological tests that included the examination of glucose and blood in the fasted state, the level of NOMA-IR index; measuring the level of microalbuminuria, creatinine of blood, glomerular filtration rate, glycated hemoglobin, cortisol and measuring lipid metavolism
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