Abstract
During the period from January to May 1957, the distribution of neutralizing antibodies against Adenoviruses Type I to Type VI according to age was investigated by conducting tissue culture (Hela) on a total of 757 serum specimens taken from healthy inhabitants in Okayama District.As a result of this investigation, the degree of prevalence of Adenovirus in Japan was clarified and compared with the distirbution of antibodies against Adenovirus in Washington Area for further study.The result of this investigation was as follows.1) The percentage of positive reaction of neutralizing antibodies according to age group in these 6 types showed almost the same changes.Namely, it was found that the percentage of positive reaction was highest in the funicular blood and lowest 6 to 12 months after birth and increased rapidly during 3 to 5 years thereafter and slowly after 6 years.This result suggests that each type of Adenovirus has prevailed very extensively in Okayama District.2) This result was compared with the distribution of antibodies in Washington Area reported by Huebner. This comparison revealed higher rates in any type of Adenovirus in any age group in Okayama District than in Washington Area.Namely, it was revealed that Adenoviruses were prevailing more extensively in Okayama District than in Washington Area.3) In Okayama District, 50% of all infants ranging in age from immediately after birth to 12 months after birth were found to be infected with at least more than 2 types of viruses and adults have been usually infected with more than 4 or 5 types of viruses.The percentage of infection in Okayama District was much higher than in Washington Area.
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