Abstract
Objective: To determine the frequency of Helicobacter pylori (HP) in patients with chronic dyspepsia referred to private laboratories in Mazar-i-Sharif city in 2019. Methods: This study is a descriptive cross-sectional study which the sampling method has performed randomly on six private laboratories in Mazari-Sharif city. The population under study consisted people with digestive disorders and a number of them had no any signs and symptoms. Subjects of study were persons that referred to serological and stool testing for HP at private laboratories in Mazar-e Sharif city in the winter season of 2019. Of course, the patients included in this study are mostly those who have been treated with gastritis tablets at one time but have not been cured. The variants of study included gender, age group, presence and absence of signs and symptoms, place of residence. The patients’ information was obtained through the patient record book and patient’s examination result sheet in which the blood serum and their stool were used for diagnosis. Results: From 108 patients were recruited for HP study, 53 people were men and 55 people women, who were used for diagnosis serologic and stool tests, which showed that 74% of patients had positive result for HP and 26% negative result for HP and these patients were between the ages of 15-65 in terms of presence and absence of sign and symptoms, 57% with loss of weight and stomach irritation, 14% with anorexia, 7% had headache and vertigo and 22% had no signs and symptoms. Conclusions: The present study on 108 who were referred to private laboratories for blood or stool examination were positive for male (39%) and negative (13%), for female (33%) were positive and (15%) negative. Likewise their age groups were different with the majority of patients being between the ages of 15-25 and the minority were 56-65 years. 57% of patient complaining gastric irritation, severe stomach pain and loss of weight. Keywords: Helicobacter pylori, gastritis, indigestion, dyspepsia, diagnostic tests, sensitivity, resistance.
Highlights
Helicobacter pylori (HP) is one of the most common chronic infections in the human stomach and has been developed in developing countries
In 1994, the International Agency for Research on Cancer, identified HP as a Group 1 carcinogen for humans and considered the most common cause of infection-related cancers, with more than 60% of gastric cancer cases being infected with this bacterium [3]
From 108 patients were recruited for HP study, 53 were men and 55 women
Summary
Helicobacter pylori (HP) is one of the most common chronic infections in the human stomach and has been developed in developing countries. HP is spring like gram negative bacterium similar to Campylobacter, which has a number of active and motive flagella in its one pole, producing urease, catalase and positive oxidase enzymes. HP is a bacterium that infect internal stomach coats. According to the Centers for Disease Control and Prevention. H. Parsa et al Evaluation of Helicobacter pylori (CDC) data in 1998, these bacteria are causing for 80 percent of gastric ulcers and 90 percent of duodenal ulcers. Parsa et al Evaluation of Helicobacter pylori (CDC) data in 1998, these bacteria are causing for 80 percent of gastric ulcers and 90 percent of duodenal ulcers They can cause other stomach problems too [1]
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