Abstract
Objective: To evaluate the effect of staying at home during the COVID-19 pandemic on serum 25(OH)D levels in children permanently residing in Ryazan. Methods: The study included 279 children aged 2 to 17, who were divided into two groups: in Group 1, serum 25(OH)D level was tested before the COVID-19 pandemic, while in Group 2, it was assessed during a pandemic. Results: The median serum 25(OH)D level in children of Group 1 was 1.4 times higher than in Group 2 (22.8 ng/ml vs. 16.6 ng/ml, p=0.004). The share of children with vitamin D (VD) deficiency during the pandemic home stay increased 1.4 times, while the percentage of children with optimal VD status decreased by three times. A statistically significant decrease in the median serum 25(OH)D during the pandemic was observed in children aged 2-3 years and 4-6 years (p<0.05). Conclusion: COVID-19 movement restrictions significantly decreased serum 25(OH)D levels in children. Keywords: Children, vitamin D, restrictive measures, COVID-19 pandemic.
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