Abstract
A series of amides of 3-hydroxy-7,7-dialkyl-7,8-dihydroindolo[2,1-a]isoquinolinecarboxylic acids have been synthesized via the reaction of 1,2,3,4-tetrahydroisoquinoline enaminoamides with p-benzoquinone. By using benzo[f]isoquinoline derivative as enamine, a less known pentacyclic system of benzo[ f ]indolo[2,1-a]isoquinoline was synthesized. The obtained amides were characterized with respect to their fungicidal activity. The most active among them was hexamethyleneimide, which was effective at a concentration of 500 μg/ml.
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