Abstract

Introduction: Overweight and osteoporosis are two common health problems in adults that often result from decreased physical activity. Biochemical markers evaluate the effects of dynamic changes on bone function and determine the response of bone metabolism to physical activity. Insulin-like growth factor-1, parathyroid hormone and alkaline phosphatase are important bone markers in bone metabolism, but there is still much ambiguity about them. The purpose of this study was to evaluate the effect of three months basketball training on Insulin-like growth factor-1, parathyroid hormone and alkaline phosphatase in 45-55 years old overweight men. Methods: 24 overweight men (47.91±2.06 years, 27.80±1.13 kg/m2) were purposefully selected based on inclusion criteria and randomly divided into control and experimental groups. The experimental group practiced basketball training three days a week, 90 min in each session, for three months. 24 h before training and 48 h after the last training session, the fasting blood sample was taken to measure insulin-like growth factor-1, parathyroid hormone and alkaline phosphatase by ELISA method. Results: Insulin-like growth factor-1 (P=0.002) and alkaline phosphatase (P=0.03) were increased after three months basketball training. However, parathyroid hormone was not changed significantly. Conclusion: It seems that three months basketball training can induce mechanical loading effects on musculoskeletal tissue and has anabolic effect on the body.

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