Abstract
Ten isosteric compounds of sulfanilamide were synthesized by replacing one or both of the two amino groups by CH3, OH or Cl (instead of F). Their comparative bacteriostatic activities were tested against E. coli und Staphylococcus aureus. The order of the precedence of the compounds are given in Table I. These facts indicate that sulfanilamide is most active among compounds tested but it is only a matter of comparison and compounds physically similar also possess considerable activities.
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