Abstract

The research was carried out in the Interdepartmental Scientific Veterinary Center of Veterinary Medicine based in the Ulyanovsk State Agricultural University. We studied the testis tumor - sertoli cell tumor, according to histological classification, in a male dog with inguinal cryptorchidism. The research goal was to study possible changes in the differentiation, hormonal and metastatic activity of sertoli cell tumor in case of inguinal cryptorchidism in comparison with this type of tumor in physiologically located testes, described in literature. The clinical examination revealed the presence of left-sided inguinal cryptorchidism as well as signs of hyperestrogenism: hyperpigmentation and non-inflammatory alopecia of scrotum, prepuce, located sym-metrically in the right and left iliac regions of the abdomen. The studied neoplasm showed the presence of a dense capsule, the absence of infiltrative growth and metastases in the regional lymph nodes, distinct secretory activity. Fragments of tumor tissue from the testis, epididymis and spermatic cord were obtained for histological examination by the means of excisional biopsy. As a result, the neo-plasm was found to be a sertoli cell tumor of a high degree of differentiation. The tissues of the epididymis showed a significant thickening of the stroma due to the proliferation of connective tissue - a sign of severe sclerosis. The mi-croslides of the spermatic cord and epididymis did not show any signs of infiltrative growth or metastatic spread of tumor cells which meant that the relative benign quality of sertoli cell tumor was found in this clinical study of inguinal cryptorchidism.

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