Abstract

The question of the pathogenesis and development of fungal endophthalmitis is an urgent research topic Purpose. Evaluation of the clinical effectiveness of treatment of patients with fungal endophthalmitis over the past 5 years using the developed surgical technology. Material and methods. In the period 2016-2021, 5 patients with fungal endophthalmitis were treated. With the fungal etiology of endophthalmitis, one patient was after a penetrating wound, 4-after corneal microtraumas with the development of keratouveitis (all after using contact lenses). Surgical treatment included taking intraocular material for examination, performing vitrectomy in the maximum possible volume, tamponade of the vitreal cavity with perfluorodecalin (for 5-14 days) and intravitreal administration of amphotericin B in 10 mcg in 0.1 ml. Results. As a result of treatment of fungal endophthalmitis, it was possible to preserve the eye as an organ in 3 patients (60%), to preserve visual functions in 1 patient (20%). Conclusion. Fungal endophthalmitis is a severe pathology of the visual organ. The prognosis for the preservation of visual functions is unfavorable, the preservation of the eye is doubtful. Key words: fungal endophthalmitis, vitrectomy, perfluorodecalin, amphotericin B.

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