КОРРЕКЦИЯ МЕТАБОЛИЧЕСКОГО СИНДРОМА У ЖЕНЩИН В ПЕРИМЕНОПАУЗЕ

Abstract

Objective: Study of the peculiarities of correction of metabolic disorders in women of the perimenopausal period Methods: 77 women were surveyed in perimenopause with metabolic syndrome (MS). Conducted analysis of hereditary prevalence and reproductive function; used clinical trails, studied carbohydrate and lipid metabolism, hormonal status; anthropometry, monitoring of arterial pressure, ultrasound of pelvic organs and liver. Results: Heredity in patients was burdened with cardiovascular diseases (58.4%), obesity (46.8%), diabetes mellitus (38.9%) and oncological pathology (18.2%). All interviewees have not given due attention to eating and enjoyed of food rich in carbohydrates in easily digestible form (81.8%). Patients showed: an increase in the body mass index (BMI) with an average value of 32±2.3 kg/m2, abdominal obesity (100%), insulin resistance (96.1%), dyslipidemia (84.4%), endocrinopathy (58.4%), hyperglycemia (55.8%), arterial hypertension (50.6%), androgen-dependent manifestations (32.5%), "Negroid acanthosis" (31,2%), steatosis of the liver (41.6%). Correction MS included a rational diet, increased motor activity, the appointment Metfogamma and Inoclim. The re-examination showed stabilization of the weight, reliable HOMA index reduction, general cholesterol content, low-density lipoprotein, and an increase of high-density lipoprotein level (p<0.05). Vegetovascular manifestations eliminated in 54.5% of women. Conclusion: Timely diagnosis and correction of metabolic disorders in women of perimenopausal age normalizes the main metabolism, eliminates the manifestations of menopause syndrome and positively affects the quality of their lives. Keywords: Metabolic syndrome, insulin resistance, lipid metabolism, carbohydrate metabolism, menopause, rational nutrition.