Abstract
A 36-year-old Japanese female with pilomatrical carcinoma is described. she noted a bean-sized asymptomatic subcutaneous nodule on her right upper arm about three years before visiting our hospital. She left the nodule as it was. But, about 2 years and a half later, the nodule rapidly enlarged and elevated. Soon later, the nodule was eroded and ulcerated. Biopsy performed at a hospital suggested malignant tumor, and she was refferd to us.At the first visit to us, an ulcerated elastic hard nodule, 77×71×21mm in size, was seen on her right upper arm.Histopathologic examination revealed that the lesion had reached the deep layer of the subcutaneous tissue. The nodule was composed of sheets and nests of basaloid cells with cystic spaces containing shadow cells. The sheets and nests were various in size and shape. The basaloid cells predominated over the shadow cells. The basaloid cells were compactly arranged. Atypical nuclei, many mitotic figures and some necrotic foci was detected in the nests of the basaloid cells. Infiltrative proliferation into the surrounding desmoplastic stroma was observed.She underwent the wide resection of the nodule. There has been no evidence of recurrence for 1 year after surgery.
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