Макроелементний обмін у лошат за гіперкальцитонінемії

Abstract

The changes of calcium, phosphorus, magnesium foals for hypercalcitoninemia was studied. In the first months of life calcium metabolism were altered. During the first month of life the majority of foals (85.7 percent) is hypocalcemia. Obviously, it is physiological, because in this period of life calcitonin promotes in osteocytes inhibition of enzymes that break down bone tissue to ensure the consolidation of the skeleton. In later life foals for hypercalcitoninemia hypocalcemia was observed less in one - and two-month old she was found in 57.1% of the foals; in three - to five-month old – at 42.9%. In the six-month old foals, values of total calcium in blood serum were within the physiological range (2.15–of 2.63 mmol/l). Relatively ionized calcium, its content in foals for hypercalcitoninemia was practically the same during the whole period of studies (0.96 ± 0.019 mmol/l in first day of life – 1.0 ± 0.014 mmol/l at six months of age). The proportion of the ionized form of macroelements to total calcium was stable and ranged from 48.8 per cent after the birth to 47.0% in 5 months old. Only six-month foals she was the lowest and amounted to 43.0% of the content of total calcium in serum. The other macroelements – phosphorus and magnesium in foals with hypercalcitoninemia were not significantly different from animals with physiological quantities of the hormone. In particular, the content of phosphorus, regardless of age, almost all animals were within the range of 0.9 to 1.18 mmol/l (only in some animal figures were less – 0.81–0.76 mmol/l). The content of magnesium in the blood serum of foals with hypercalcitoninemia was in the range of 0.91 – of 1.16 mmol/l.