Гестационная динамика содержания и баланса эссенциальных микроэлементов в сыворотке крови и эритроцитах женщин разного репродуктивного возраста, рожающих впервые

Abstract

The objective: to study dynamics of software of serum and erythrocyte with essential microelements (iron, copper, zinc, cobalt, magnesium, manganese) during pregnancy in women of different reproductive age in a case of the first delivery. Patients and methods. The definition of essential microelements conducted in serum and red blood cells in 44 pregnant women of early and middle reproductive age who gave birth for the first time. Pregnant women of reproductive age were respectively 16.33±0.21 and 24.67±0.37 years. The study was conducted in the first, second and third trimesters of pregnancy at 10.26±0.34, 23.23±0.51 and 36.08±0.59 weeks of gestation, respectively. For determination of microelemennts used spectrophotometry С – 115M1. Results. For the course of pregnancy in women of middle reproductive age was typical considerable dynamism of serum and erythrocyte content of microelements. During pregnancy significantly improves the condition of serum iron pool. Serum level of other essential microelements to the end of pregnancy significantly decreased, especially magnesium – three times, cobalt and manganese – twice, zinc had a tendency to reduce. Reduction of essential trace elements (magnesium, cobalt, manganese, zinc) is due to their active use of fetus especially in the third trimester of pregnancy. In women of early reproductive age for the end of the third trimester of pregnancy, we found depletion of serum and erythrocyte content of iron and manganese, which can contribute to anemia. Increasing in the cobalt content in both environments shows voltage in hematopoietic system. Conclusion. With the aim to examine the features of microelement software of fetus and development of methods of its correction, it seems appropriate to study the content and balance of essential trace elements in the mother-placenta-fetus. Key words: essential microelements, pregnant women, reproductive age, the first birth.