Abstract

맥문동, 차가버섯, 감초, 흑삼, 백출, 백복령, 당귀, 숙지황, 천궁, 작약의 추출물을 이용한 한방소재로 에센스와 크림을 제조하여 눈가의 주름개선 효과를 평가하였다. 평균연령 44.8세의 한국인 중년여성 6명을 대상으로 에센스 사용 후 크림 사용으로 매일 2회씩(아침, 저녁), $1cm^2$ 당 2mg씩, 4주간 연속 사용하도록 한 다음, 4주 경과 후 눈가 주름의 모사판을 제작하여 영상 분석하였다. 눈꼬리 주름 모사판 영상분석 결과, 에센스와 크림 사용 4주 후 주름 R1은 $3.22{\pm}0.85$ 에서 $2.38{\pm}0.32$ , R2는 $3.08{\pm}0.83$ 에서 $2.22{\pm}0.32$ , R3는 $2.29{\pm}0.64$ 에서 $2.29{\pm}0.64$ , R4는 $0.44{\pm}0.14$ 에서 $0.44{\pm}0.14$ , R5는 $0.98{\pm}0.21$ 에서 $0.98{\pm}0.21$ 로 유의하게 감소하여(P 【This study evaluated anti-wrinkle effect for eye using essence and cream containing extract of Liriope platy phyllla, Inonotus obliquus, Glycyrrhiza glabra, black ginseng, Atractylodes japonica, Poria cocos Wolf, Angelica gigas, Rehmanniae Radix Preparata and Cnidii Rhizoma, Paeonia lactiflora. 6 female adults on average at the age of 44.8, applied cream after essence under the normal conditions of use on the crow's feet area, twice a day (in the morning and evening), 2mg/ $1cm^ 2$ for 4weeks. After 4 weeks, the replica of eye wrinkle was made and analyzed the image. The result was that eye wrinkle was decreased in R1( $3.22{\pm}0.85$ to $2.38{\pm}0.32$ ), R2( $3.08{\pm}0.83$ to $2.22{\pm}0.32$ ), R3( $2.29{\pm}0.64$ to $2.29{\pm}0.64$ ), R4( $0.44{\pm}0.14$ to $0.44{\pm}0.14$ ), and R5( $0.98{\pm}0.21$ to $0.98{\pm}0.21$ )(P】

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