Функциональные особенности зрительного анализатора у пациентов с хронической ишемической нейрооптикопатией, ассоциированной с гемодинамически значимым атеросклеротическим стенозом внутренней сонной артерии, после проведенной каротидной эндартерэктомии

Abstract

Purpose. To evaluate effect of carotid endarterectomy (CE) in long-term follow-up period on course of chronic ischemic optic neuropathy (CION) associated with hemodynamically significant atherosclerotic internal carotid artery (ICA) stenosis. Material and methods. The object of study was 30 patients (30 eyes) with CION associated with hemodynamically significant atherosclerotic ICA stenosis. All patients underwent study of visual evoked potential (VEP), optical coherence tomography, Doppler ultrasonography of ophthalmic artery (OA) before and after ICA CE. Results. By the end of observation period (12 months), in patients with CION, despite the improvement blood flow in OA, there was deterioration in VEP and decrease in the thickness of the peripapillary retinal nerve fiber layer, the cause of which can be considered imbalance of energy metabolism that negatively affects the ganglion cells axons, leading to their death. Conclusion. Our studies show that further studies are needed to study the effect of ICA CE on the course of CION. Keywords: chronic ischemic optic neuropathy, ocular ischemic syndrome, hemodynamically significant internal carotid artery stenosis, visual evoked potential, optical coherence tomography.