Анализ ганглиозных клеток сетчатки по данным оптической когерентной томографии у пациентов после витрэктомии по поводу регматогенной отслойки сетчатки

Abstract

The study included 59 eyes after vitrectomy with silicone oil and gas tamponade. The 1st group (31 eyes) consisted of cases with silicone oil 1300 cSt tamponade, the 2nd group (28 eyes) – cases with C2F6 gas tamponade. Perpose. To compare changes in morphological parameters of ganglion cells and the morphological structure of the retina after vitrectomy with gas and silicone oil tamponade due to rhegmatogenous retinal detachment. Results. BCVA in the 1st group was reduced compared to the 2nd group, amounting to 0.4 [0.2; 0.5] in the 1st group and 0.5 [0.3; 0.6] (U = 242.500, p = 0.044) in the 2nd group. In the 1st group ERM occurred 4.1 times more often than in the 2nd group (χ² = 4.391, df = 1, p = 0.036). Macular edema in the outer nuclear layer was detected only in the 1st group in 16 % of cases (χ² = 4.766, df = 1, p = 0.029). Macular edema in the inner nuclear layer in the 1st group was 5.7 times more common than in 2nd group, amounting to 22.6 % and 4 %, respectively (χ² = 4.325, df = 1, p = 0.029). Ellipsoid zone defect was detected in 22.6 % of cases in the 1st group and in 32 % of cases in the 2nd group (χ² = 0.835, df = 1, p = 0.361). The focal loss volume of retinal ganglion cells in the 1st group was 8.5 times higher than in the 2nd group (U = 158.500, p = 0.009) A statistically significant difference was obtained for the Intra Eye GCC parameter, amounting to -5.0 [-8.25; 1.0]* in the 1st group and 0.0 [-3.0; 6.0] in the 2nd (U = 146.500, p = 0.004). Conclusion. According to visometry in the postoperative period for rhegmatogenous retinal detachment using silicone oi tamponade with a duration of 80.0 [59.0; 120.0] associated with a lower functional result compare to gas tamponade, accompanied by a more frequent formation of ERM, cystoid macular edema and an increase in focal loss volume of ganglion cell complex compared to gas tamponade.