Abstract
In maxillofacial region, reconstruction of defects after inflammation, trauma, tumor resection and congenital anomaly should be functional and aesthetic. Meanwhile, recent approaches using regenerative medicine have shown great potential, enabling functionally and esthetically-satisfying reconstructions with less invasive manner. This review describes such regenerative medicine of bone in maxillofacial region, including transplantation of particulate cancellous bone and marrow (PCBM) in combination with a titanium mesh tray, and custom-made artificial bone (CT-Bone). Our preclinical and clinical study on tissue-engineered cartilage for patients with cleft-lip and nose is also covered.
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