ОСОБЕННОСТИ КОСТНОЙ БИОДИНАМИКИ У ДЕТЕЙ С КОСТНЫМИ КИСТАМИ

Abstract

Background. Taking into account the peculiarities of bone biodynamics, and the fact that in the period from 5 to 16 years bone mineral density increases by 3 times, which coincides with the age period for the detection of bone cysts in children, the study of bone mineral density indicators, the level of vitamin D, which mainly regulates bone formation, in patients with bone cysts is relevant today. The purpose of the study. To study the indicators of bone mineral density and total vitamin D in children with bone cysts, to analyze the relationship between the occurrence of bone cysts and osteogenesis disorders. Material and methods. The indicators of the condition of bone tissue in children diagnosed with a bone cyst were studied: bone mineral density and vitamin D levels in the blood were determined in 25 children. In total 83 patients with other orthopedic and traumatological pathology were examined as comparison groups: in 42 patients the index of bone mineral density was determined, in 41 patients the amount of vitamin D was assessed. Bone mineral density was determined by double X-ray absorptiometry and computed tomography. The method for determining total vitamin D is based on a solid-phase sandwich-type enzyme immunoassay. Results. In the examined patients diagnosed with a bone cyst, 36% had their bone mineral density index within the age norm, 36% had osteopenia and 28% of children had osteoporosis. In the comparison group, 21.5% of children showed changes in bone mineral density, 78.5% had bone mineral density within the age norm. When studying the level of total vitamin D in the blood serum of patients with bone cysts, the following results were obtained: in 24% of patients, the level of vitamin D was within the age norm, in 72% vitamin D insufficiency and in 4% - vitamin D deficiency were detected. The study of the level of total vitamin D in the blood serum of patients in the control group showed the following results: 68% of patients had vitamin D levels within the age norm, 29% had insufficiency and 3% had deficiency of vitamin D. Conclusions. The analysis of the results of densitometry and the level of total vitamin D in the blood of patients with bone cysts showed that there was a statistically significant decrease in their bone mineral density and total vitamin D compared to children from the comparison group. Thus, children with bone cysts have a higher risk of a decrease in bone mineral density and the level of total vitamin D in the blood; therefore, in addition to appropriate surgery, it is also necessary to determine the level of bone mineral density and total vitamin D for the purpose of their correction.