Когнитивные особенности хронической обструктивной болезни легких у пациентов с алкогольной зависимостью

Abstract

Chronic obstructive pulmonary disease (COPD) is a significant public health problem due to its widespread prevalence. It becomes a medical and social burden for both society and the patient. To what extent comorbid alcoholism is able to influence the features of the clinical course of COPD remains an open issue. The study aimed to reveal the impact of alcoholism on the level of COPD subjective symptoms in patients with different compliance. Materials and methods. 147 men with COPD in the age of 40―88 years were examined. The study relied on spirometry criteria, mMRC, CAT, domestic questionnaire of adherence to therapy, 6-minutes walking tests. It also established the stage of alcohol disease. The inhalation therapy was clarified during the interview, the episodic and systemic omissions fixed. Results and discussion. We observed the trend to subjective COPD symptoms underestimation in patients with the II, III stages of alcohol disease. Alcohol disease did not affect subjective symptoms in patients with stages III, IV of COPD. The compliance level and subjective symptoms severity showed no interrelation in patients suffering from alcoholism. This emphasized the absent association between the high level of compliance and critical self-state perception in patients with concomitant diseases. Regardless of the concomitant dependence, systemic omissions were rarely observed in patients receiving inhalers with a lower dosage frequency. Conclusion. The poor informativity of mMRC dyspnea scale and CAT-test was demonstrated in patients with mild and moderate COPD and severe alcoholism. The high level of compliance showed no impact on this tendency. Using single dose per day regimen was associated with a better compliance to recommendations, regardless of alcohol adherence.