Abstract

We investigated the functional state of thyroid and parathyroid glands in 227 children with ecologically determined bone diseases. Triiodothyronine, thyroxin, calcitonin and parathormone level of these children was determined by immunoreactive method. Bone mineral density and bone system degree of changes were measured by ultrasound densitometry: bone mineral density < 67 % - osteoporosis, bone mineral density from 80 % to 67 % - osteopenia, 100 +/- 20 % - normal bone mineral density, 120 % and more - osteosclerosis. Parathormone level was significantly decreased in all children with osteoporosis and osteopenia from ecologically polluted regions. Subclinical hypothyroidism is a marker for radiation polluted environment, and subclinical hyperthyroidism is a marker for chemically polluted environment.

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