Abstract
Long terme rythromicin (EM) therapy has been reported to be useful in chronic sinusitis. We investigated the clinical effectiveness of low dose long term clarithromycin (CAM) therapy for chronic sinusitis in children. Children were treated with 100 or 200mg of CAM perday for 4 to 18 weeks.1) Total clearing of subjective symptons was revealed in 93.8% of the patients.2) Total improvement rates were 93.8% for rhinoscopic findings and 90.6% for X-ray appearance.3) The clinical effectiveness of CAM therapy tended to be better than that of EM therapy.4) No significant side effects were noted during the therapy.It is the refore concluded that CAM therapy is very useful in the treatment of chronic sinusitis in children.
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