Abstract
We report a case of malignant chondroid syringoma affecting the preauricular portion of the left ear of a 67-year-old man. There were submental lymph node metastasis and multiple pulmonary metastases two months later. The local recurrence occurred at the primary site about 12 months after the initial insufficient surgical procedure. We suspected clinically squamous cell carcinoma was suspected. However, the findings of the histopathological, immunohistochemical and ultrastructual examinations for reccurent tumor led us finally to make a diagnosis of malignant chondroid syringoma. Patient received electron beam radiation followed by administration of chemotherapeutic agents including CDDP, 5-FU and irinotecan and taxotere. We discussed the usefulness of such combination therapy, particulary the chemotherapeutic agents including taxotere.
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