НОВАЯ КОРОНАВИРУСНАЯ ИНФЕКЦИЯ COVID-19 У ПАЦИЕНТКИ С АУТОИММУННЫМ ПОЛИГЛАНДУЛЯРНЫМ СИНДРОМОМ (клинический случай)

Abstract

Background.More than half of those infected with the new coronavirus infection COVID­19 carry the disease in a mild or asymptomatic form. Patients over 60 years of age and those with comorbid chronic diseases, such as respiratory, cardiovascular, diabetes, oncological and autoimmune diseases, are susceptible to more severe forms of the disease. Aim.The aim of the study was to demonstrate the stages of clinical picture development, methods of diagnosis and treatment of the new coronavirus infection COVID­19. Material and methods. We present a clinical case of a new coronavirus infection COVID­19 in a 73­year­old patient with autoimmune polyglandular syndrome. Results and its discussion. Aggravating background represented by arrhythmic syndrome and autoimmune polyglandular syndrome contributed to the development of a severe form of new coronavirus infection COVID­19 in the patient. Complex multivector therapy aimed at pathogenetic and symptomatic treatment, according to the guidelines, in combination with magnesium and potassium medications, as well as immune­modulating therapy contributed to the patient’s recovery and rehabilitation. Conclusion. Treatment with glucocorticoids for new COVID­19 coronavirus infection significantly improves the outcome of the disease. At the same time, glucocorticoid therapy can lead to progression of arrhythmic syndrome, development of drug­induced hypercorticoidism, and «withdrawal» syndrome. Prevention and treatment of heart rhythm disturbances is the application of potassium and magnesium medications in sufficient doses. Gradual withdrawal of glucocorticoids over a long time under the supervision of an endocrinologist will help to restore the hypothalamic­pituitary­adrenal axis.