Abstract

Autoimmune polyglandular syndrome type III (subtype IIIa) has polygenic inheritance and is most common among other polyendocrine autoimmune syndromes. As the main feature polyglandular syndrome-IIIa includes one of the autoimmune thyroid diseases combined with other autoimmune endocrine diseases that are not included in the polyendocrine (polyglandular) autoimmune syndromes types I and II.Because of the rarity of the reported cases of autoimmune polyglandular syndromes, we present the case of patient, diagnosed with type IIIa autoimmune polyglandular syndrome. In the described case the first recorded autoimmune disease was autoimmune diabetes mellitus type I, followed by autoimmune thyroiditis. Based on the occurrence of polyglandular syndrome-IIIa type, it is necessary to emphasize the need for registration and dynamic monitoring of the patients with identified autoimmune diabetes mellitus type I or autoimmune thyroid diseases in order to early diagnosis the combination of these organ-specific autoimmune diseases.

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