Abstract
Hypothyroidism is usually manifested by a wide range of symptoms from various body systems, including the nervous system. It was found that approximately 30% of patients with decreased thyroid function suffer from cephalgia, which is associated with a thyroid hormone deficiency. Both primary and secondary hypothyroidism can not only lead to secondary cephalgia but also aggravate pre-existing primary cephalgia, most commonly migraine. It is known that cephalgia is more common in women, especially if there is a history of migraine. In everyday clinical practice, cephalgia associated with hypothyroidism is rarely diagnosed as an independent form of secondary cephalgia. More commonly, primary cephalgia, such as migraine and tension headache, are regarded as concomitant diseases in patients with decreased thyroid function. To date, data on the association between hypothyroidism and migraine, as well as hypothyroidism and tension headache are contradictory and it is not always possible to determine which process is primary or secondary. The pathophysiological basis explaining the association between hypothyroidism and cephalgia/migraine has not yet been studied. KEYWORDS: hypothyroidism, cephalgia, migraine, tension headache, thyroid-stimulating hormone, hypothalamus, levothyroxine, Hashimoto's thyroiditis, Hashimoto's encephalopathy, preventive migraine treatment. FOR CITATION: Parkhomenko E.V., Ekusheva E.V., Kulikova S.I. Сephalgia and hypothyroidism. Russian Medical Inquiry. 2023;7(10):630–634 (in Russ.). DOI: 10.32364/2587-6821-2023-7-10-4.
Published Version
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