Abstract

Background: Evidence-based medicine (EBM) is now a trend, but its information infrastructure has not been well developed in Japan, as seen by the fact that The Cochrane Library/CENTRAL does not list enough Japanese randomized controlled trials/controlled clinical trials (RCTs/CCTs). This situation should be improved.Objective: To describe the Database of Japanese Randomized Controlled Trials (J-RCT) project, funded by the Ministry of Education, Science, Sports and Culture of Japan; to register citations in English of Japanese RCTs with The Cochrane Library/CENTRAL.Method: RCTs/CCTs citations in the journal Rinsho Hyoka (Clinical Evaluation) from 1982 to 1995 have been handsearched according to the handsearch manual of the Cochrane Collaboration and processed into a ProCite file utilizing the JICST-E file of the Japan Science and Technology Corporation (JST), then sent to the New England Cochrane Center.Result: 119 citations were registered with The Cochrane Library 1999 Issue 3, and a data processing system has been developed from the JICST-E file, including their problem-solving methods and future perspectives.Discussion: The role of J-RCT and the significance of cooperation with JST have been recognized. This project is expected to encourage Japanese medical journals to improve their reporting of clinical trials.

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