Abstract
In Ukraine, among chronic diseases, pathology of the musculoskeletal system is one of the most frequent problems, and about 3.5 million people have problems with the musculoskeletal system and its various complications, which require continuous therapy throughout life. Aim. Generalization of the results of a comprehensive sanitary and hygienic assessment of the safety for consumers of a dietary supplement created to support the normal functioning of joints; data analysis of electronic publishers Scopus, Web of Science, PubMed, other foreign and domestic sources of scientific information on the research topic. Materials and Methods. The dietary supplement "Rheumacare Ultra" has been tested for the content of heavy metals and pesticides for compliance with the State Sanitary Rules and Regulations of Ukraine. The microbiological safety of the dietary supplement was controlled by the content of mesophilic aerobic and facultative anaerobic microorganisms. The method of ultra-high-performance high-speed mass spectrometric liquid chromatography with electron spray ionization (UPLC-MC/MC, Waters, USA) and the gas chromatography method were used to determine the content of pesticide residues; the content of lead, cadmium, mercury was determined by the atomic emission method (instrument ‒ atomic emission spectrometer "SHIMADSU ICPE ‒ 9820"). Results. Based on expert assessment of documentation, analysis of data sources of scientific information, results of sanitarychemical, radiological and sanitary-microbiological studies, it was established that dietary supplement "Rheumacare Ultra" ("Rheumacare Ultra") is safe for the health of consumers and can be used for purpose: to promote the normalization of metabolism, optimization of the chemical composition of the diet, creation of optimal dietary conditions to support the normal functioning of the musculoskeletal system, in particular ‒ joints; to purposefully affect the growth of the level of adaptation capabilities of the human body in conditions of constantly increasing harmful effects of the environment. Conclusions. Assessing the safety of traditional Ayurvedic recipes is a difficult task due to the multicomponent composition of organic-mineral complexes and the lack of complete information on the chemical structure of biologically active components of endemic plants and their impact on human health. Keywords: dietary supplements, sanitary and hygienic assessment, musculoskeletal system, joints.
Published Version
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