О вакцинации подростков против туберкулеза

L.A Zazimko,I.V Krasil’Nikov,A.M Korolyuk

doi:10.15690/vsp.v13i1.933

L.A Zazimko, I.V Krasil’Nikov + Show 1 more

Open Access

https://doi.org/10.15690/vsp.v13i1.933

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Abstract

The questions of vaccination and revaccination with BCG vaccine, mass screening of children and adolescents with Mantoux test in order to reveal risk groups for development of active tuberculosis and further individual diagnostics among such patients are discussed in this article. The data on efficacy of vaccination against tuberculosis in the Russian Federation are covered. The authors represented information on negative experience of the cancellation of the revaccination against tuberculosis in the Republic of Belarus which led to increase of tuberculosis prevalence. The characteristics of the immune response during adolescence due to the risk of tuberculosis development are considered. It was concluded that special features of the adolescents immune system, negative experience of the Republic of Belarus on cancellation of BCG revaccination at the age of 14 years old, refusals of the adolescents noninfected with mycobacteria to undergo second revaccination with BCG at the age of 14 years old can lead to increase in active forms of tuberculosis among adolescents. Under the conditions of the increasing resistance of mycobacteria to antituberculous agents this is fraught with lethal outcomes.

Highlights

Туберкулезная инфекция в условиях эпидемического неблагополучия представляет существенную угрозу для детей и подростков
The questions of vaccination and revaccination with BCG vaccine, mass screening of children and adolescents with Mantoux test in order to reveal risk groups for development of active tuberculosis and further individual diagnostics among such patients are discussed in this article
The authors represented information on negative experience of the cancellation of the revaccination against tuberculosis in the Republic of Belarus which led to increase of tuberculosis prevalence

Summary

Introduction

Туберкулезная инфекция в условиях эпидемического неблагополучия представляет существенную угрозу для детей и подростков. It was concluded that special features of the adolescents immune system, negative experience of the Republic of Belarus on cancellation of BCG revaccination at the age of 14 years old, refusals of the adolescents noninfected with mycobacteria to undergo second revaccination with BCG at the age of 14 years old can lead to increase in active forms of tuberculosis among adolescents. [1] был проведен корреляционный анализ заболеваемости туберкулезом среди лиц, привитых и не привитых вакциной БЦЖ.

Results

Conclusion