Abstract
A clinical case of Muckle-Wells syndrome in a 3-years old child is presented. Muckle-Wells syndrome is among the group of human autoinflammatory diseases (cryopyrin-associated periodic syndromes) – rare genetic diseases characterised by systemic inflammation in absence of other revealed autoimmune and infectious reasons. The disease is characterised by the combination of fever, skin rash and other symptoms accompanied by development of potentially disabling or life-threatening complications. The clinical case presented illustrates the course as well the difficulties in diagnosis and treatment of Muckle-Wells syndrome.
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