Abstract
Abstract. Primary breast lymphoma is an unusual clinical entity accounting for 0.05-0.53% of all breast neoplasms. The usual presentation includes a painless palpable mass similar to that of breast carcinoma. Diffuse large B-cell lymphoma is the most common identifiable type of plasmablastic lymphoma based on the histopathological examination. We report an unusual case of a 47-year-old Belarusian woman who presented with a 3-month history of a painless mass in the left breast. A biopsy revealed diffuse infiltration of lymphoid cells. The immunohistochemical biomarkers confirmed the diagnosis of a non-Hodgkin's diffuse large B-cell lymphoma. After completing the chemotherapy, the patient is on follow-up, and at 48 months she is alive without disease activity. This case demonstrates the importance of histological verification for treatment. An integrated approach, including the analysis of clinical and anamnestic data, the results of histological and immunohistochemical analysis, allows for modern differential diagnosis of rare breast tumors.
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