Abstract
Background. Early diagnosis of benign liver tumors (BLT) is based on the use of methods for visualization of focal lesions of the liver. The final diagnosis of BLT is established using a comprehensive diagnosis, which includes a morphological study. The goal is to present the morphological characteristics of the BLT diagnosed in the Grodno region. Material and methods. The object of the study was liver biopsy sample obtained by performing aspiration liver biopsy in patients with focal liver disease, liver fragments excised during surgery, and also sectional material. Results. A detailed description of the morphological signs of the most frequently occurring focal lesions of the liver, referred to the BLT, is presented. Among the main BLT are tumors of epithelial and mesenchymal origin: hepatocellular adenoma, adenoma of the intrahepatic bile ducts, cystadenoma of the intrahepatic bile ducts, focal nodular hyperplasia, mesenchymal hamartoma, infantile hemangiendothelioma, hemangioma, adenomatous hyperplasia, liver damage by hematopoietic and lymphoid tissue, cysts, polycystic liver are different. Conclusion. For their morphological features BLT are different from malignant. However, under certain conditions, some BLT can increase to critical sizes, disrupt liver function, lead to complications in the form of internal bleeding and other negative consequences. The most unfavorable outcome of a number of BLT is their malignancy, which requires continuous monitoring of focal liver lesions by visualization methods, the study of molecular-genetic markers of early malignancy, and the use of morphological study of BLT (according to indications).
Highlights
Diagnosis of benign liver tumors (BLT) is based on the use of methods for visualization of focal lesions of the liver
The goal is to present the morphological characteristics of the BLT diagnosed in the
liver biopsy sample obtained by performing aspiration liver biopsy in patients
Summary
Ранняя диагностика доброкачественных опухолей печени (ДОП) основана на применении методов визуализации очаговых поражений печени. Цель – представить морфологическую характеристику ДОП, диагностируемых в Гродненском регионе. Среди основных ДОП представлены опухоли, имеющие эпителиальное и мезенхимальное происхождение: гепатоцеллюлярная аденома, аденома внутрипеченочных желчных протоков, цистаденома внутрипеченочных желчных протоков, фокальная нодулярная гиперплазия, мезенхимальная гамартома, инфантильная гемангиоэндотелиома, гемангиомай, аденоматозная гиперплазия, поражение печени опухолями кроветворной и лимфоидной ткани, кисты, поликистоз печени другие. Самым неблагоприятным исходом ряда ДОП является их малигнизация, для чего необходим постоянный мониторинг очаговых поражений печени методами визуализации, исследование молекулярно-генетическими маркеров ранней малигнизации и применение морфологического исследования ДОП (по показаниям). В печени также формируются гемангиома, лимфангиома, лимфангиоматоз, ангиомиолипома, эпителиоидная гемангиоэндотелиома, саркома Капоши, липома, фиброма и другие, строение которых принципиально не отличается от аналогичных опухолей других локализаций [3]. Цель исследования – представить морфологическую характеристику ДОП, диагностируемых в Гродненском регионе
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