人間ドック受診者における泌尿器がん（腎がん・膀胱がん・前立腺がん）罹患率およびリスク因子に関する検討

Abstract

(Objective) We studies morbidity and risk factors related to urinary cancers (renal, bladder, and prostate) from health screening interviews and results. (Subjects and Methods) We extracted data from 48,454 adults who underwent health screenings between April 2006 and March 2008.Of particular interest were examinees who were newly diagnosed with urinary cancer after the consultation. The data examined included factors such as sex, age, total years of smoking, body mass index (BMI), drinking status, weight gain (>10 kg from the age of 20), accumulation of stress, sleep condition/habits, adequate dairy product intake, hypertension, diabetes mellitus, and dyslipidemia. (Results) The numbers of patients who were diagnosed with renal, bladder, or prostatic cancer were 45, 47, and 215, respectively. The corresponding morbidity rates were 0.093%, 0.097%, and 0.721%. From the results of the univariate analysis, renal cancer was found to be significantly correlated with the male gender, old age, high BMI, drinking, weight gain, and hypertension. In addition, we found a significant correlation between bladder cancer and male gender, old age, total years of smoking, and drinking. Prostate cancer was significantly correlated with old age, total years of smoking, weight gain, accumulation of stress, and dyslipidemia. The multivariate analysis demonstrated a significant correlation between renal cancer and old age, between bladder cancer and both male gender and old age, and between prostatic cancer and both old age and dyslipidemia. (Conclusion) Old age was identified as a common risk factor that is significantly and independently correlated with urinary cancers.