БИОХИМИЧЕСКИЙ ПРОФИЛЬ КОБЫЛ В ПЕРВЫЕ 2 МЕСЯЦА ЖЕРЕБОСТИ

Abstract

Getting healthy offspring depends on the health of the mother. Changes in the biochemical profiles of mares can be markers of the threatened state for the embryo and fetus. There were no significant differences in the concentration of total protein, albumin, globulin, urea, glucose, triglycerides in non-pregnant mares and mares 2 months of pregnancy. The activity of AST and ALT also did not differ. There was a significant increase in cholesterol in the second month of pregnancy compared with the first month - from 2.1 ± 0.12 to 2.4 ± 0.09 mmol/L (p <0.05). The activity of LDG and GGT significantly increased in mares in the second month of pregnancy compared with non-pregnant mares. LDG activity increased by 10%, and GGT increased by 27% (p <0.05). There was a significant increase in the concentration of creatinine in mares from the first month of pregnancy. The concentration of globulins was significantly lower by 9% (p <0.05) in the mares aborted later. Also, aborted mares showed an increased concentration of triglycerides 0.29 ± 0.03 mmol/L and cholesterol 2.8 ± 0.25 mmol /L compared with mares that successfully completed the pregnancy 0.20 ± 0.04 mmol/L and 2.4 ± 0.08 mmol /L, respectively (p <0.05). An increase in the activity of enzymes of protein-carbohydrate metabolism in mares at 2 months of gestation, with unfavorable pregnancy as compared with mares that brought healthy foals, was noted. It should be noted that all the studied biochemical parameters were within the reference values. Monitoring the biochemical status of mares before mating and in the first 2 months of pregnancy will allow identifying animals with an unfavorable prognosis of pregnancy and taking measures, for example, to adjust feeding.