АРТЕРИАЛЬНАЯ ГИПЕРТЕНЗИЯ В ПОСТМЕНОПАУЗЕ - КОРРЕЛЯЦИОННЫЕ ПАРАЛЛЕЛИ

Abstract

Arterial hypertension is probably one of the most widespread diseases. According to statistics, the prevalence of AH at the age of 45–54 years among women is 58%, and at the age of 55–64 years it increases to 74.5%. Given the fact that the antihypertensive drugs are provided in the age group of 55–64 years, the order of 80% provides that the effectiveness of the use of drug therapy is only 30%. It is at this age that the postmenopause period occurs. On average, the duration of postmenopausal varies from 5 to 6 years and can last up to 65–69 years. Compared with men of the same age group, cardiovascular diseases are significantly less frequently affected. The presence of cardinal changes in the mechanism of occurrence and course of the pathology of the cardiovascular system in men and women, primarily due to the general differences and cardioprotective effects of ovarian hormones. It has been established that in the period of postmenopause a significant increase in the frequency of arterial hypertension occurs in women. Hypoestrogenism plays a significant role in the formation of arterial hypertension in this cohort of patients, and this affects the endothelium leading to its dysfunction, and its implementation is carried out through the components of the metabolic syndrome. From an analysis of the literature, it can be seen that the effect of hormone replacement therapy should be positive. Nevertheless, it should be noted that the development of arterial hypertension in postmenopause is a complex and multifaceted process.