Abstract
Purpose: perform a retrospective review and generalization of practice-oriented scientific research of the SBR Center in the field of radiation medicine in the period 2000-2021. Material and methods: The object of research of the SBR Center is the population of the Seversk and the personnel of the Siberian Chemical Combine (SCC). The basis for scientific research of the SBR Center is the regional medical and dosimetric register of population of the Seversk and personnel of the SCC, the bank of biological material of population of the Seversk and personnel of the SCC, as well as regular participation in the organization and conduct of periodic medical examinations of SCC personnel. Results: The assessment of morbidity and mortality from malignant neoplasms of the personnel of the nuclear industry enterprise and the population of the observation zones showed no increase in their risk during chronic technogenic exposure in the range of “small” doses. Malignant neoplasms of the digestive, respiratory, urinary and reproductive systems make the greatest contribution to the structure of oncological morbidity among the personnel of the nuclear industry enterprise and the population of the observation zones. The SBR Center was the first in the world to obtain data on the significant role of ionizing radiation in combination with traditional risk factors for the development of coronary heart disease in the increased incidence of myocardial infarction among SCC personnel. The established fact is the basis for the creation of a comprehensive program for the diagnosis and prevention of diseases of the circulatory system among the personnel of the SCC, which is being effectively implemented. The modern strategy for the prevention of non-communicable socially significant diseases developed at the SBR Center among workers at nuclear facilities and the population of observation zones (on the example of the Seversk population) includes an effective system for identifying pathological conditions, their timely correction and subsequent monitoring, which is an innovative form of work on the organization of health care and the strengthening of public health in order to increase life expectancy and ensure professional longevity. Conclusion: SBR Center performs fundamental and applied research in topical areas of radiobiology, radiation medicine, epidemiology, radiation safety and public health organization. Over the years, a significant scientific reserve has been created, a unique team has been formed, the material and technical base has been developed, and significant results have been achieved, recognized by the domestic and international scientific community.
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