Abstract

The publication presents the results of morphological study of patients with chronic polypous rhinosinusitis (ChPR). ChPR is characterized with a chronic productive type of inflammation of the nasal mucosa and paranasal sinuses, with the formation and growth of polyps. In this study, we examined 70 people (50 patients in the study group and 20 patients in the control group). In this work, the authors found the polypous changes in the tissue, three types of the nasal cavity polyps. 1. Edematous polyps – histological signs: an edematous polyp stroma containing a small number of fibroblasts and connective tissue fibers, due to which the intercellular space has a spongy, loose appearance. In the depth of the polypous tissue there are areas containing single glands, cysts. 2. Allergic (eosinophilic) polyps – histological signs: the presence of infiltrates with a significant number of eosinophils, alongside with monocytes and mast cells. 3. Fibrous (fibrous-vascular, fibrocystic, fibrous-glandular) polyps – histological signs: the stroma has dense compact structure, it is made of a great number of fibroblasts and surrounding connective tissue fibers. The stroma has a large number of various caliber vessel profiles.

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