Abstract
Presented is a complex treatment of a patient with acute amitriptyline and cyclodole poisoning using enterosorption, intestinal lavage and hemosorption on a new column with a synthetic sorbent. For hemosorption, a column with a two-layer synthetic polymer was used, developed for selective sorption of cytokines by direct hemoperfusion. Quantitative measurements of levels of amitriptyline and cyclodole before and after the column, as well as before haemosorption and after haemosorption, showed a high effectiveness of the sorbent in removing toxicant from the blood. The use of 6-hour hemosorption allowed to reduce the level of amitriptyline from the initial by more than 4 times and the level of cyclodole by more than 3 times to therapeutic levels and obtain a pronounced positive clinical effect in the complex treatment of a patient with severe poisoning.
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