Abstract

Management of COVID-19 patients with drug-induced liver lesions requires a comprehensive approach to treatment with correction of metabolic disorders and prevention of adverse events. We describe our experience with using Remaxol, a drug with hepatoprotective, antihypoxic, antioxidant, and cytoprotective effects. It is applied for hepatotropic support in COVID-19 patients receiving antiviral therapy. Intravenous infusions with Remaxol (400 mL) in comprehensive treatment of COVID-19 patients promoted normalization of liver function tests, which made it possible to continue antiviral therapy without dose correction and interruptions. Remaxol was well tolerated and caused no side effects; none of the patients required its cessation. Key words: hepatotoxicity, hepatoprotectors, Remaxol, COVID-19

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