Редкие опухоли языка. Опухоль Абрикосова: клиническое наблюдение

Abstract

Granular cell tumor (GCT; Abrikossoff’s tumor; Myoblastoma) is a rare tumor that can affect various regions of the body, such as skin, soft tissues, breast, nervous system, gastrointestinal tract, urinary bladder and lungs. GCT in the head and neck region, which represents 45% to 65% of all the involved sites, is encountered most commonly in the oral tongue, especially on its anterior one third. A 36-year-old male, with a chief complaint of a slow-growing mass on the back of the tongue for 2.5 years. It was not associated with pain or dysphagia. There was no history of any significant medical or surgical illness in the past. He was a smoker and social drinker with fair oral hygiene. No cervical lymphadenopathy on regional examination. On intraoral examination, a round mass of about 0.8x0.8 cm on the back of the tongue. The patient was advised for the MRI which showed the round heterogeneous structure with unclear and non-smooth contours. We then performed the wide excision of the mass under GA and the specimen was sent for histopathological examination. postoperative period was uneventful and the lesion healed well. Thus the final diagnosis of Granular Cell tumor of tongue was made. The Tumors cells were immunopositively for S-100 protein and CD68; immunopositively for CKAE1/AE3, Ki67, Desmin. In conclusion: they are 3 important steps in the management rare tumors of the tongue: correct using of diagnostic algorithm, histopathologic examination, using this results for tactics and strategy of managing the patient.